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According to research, the ongoing uncertainty over whether hydroxychloroquine can successfully treat COVID-19 appears to have eroded demand considerably among hospitals and across the globe. Hydroxychloroquine is a drug that is approved to treat malaria, analogous to chloroquine. However, it is associated with less significant side-effects. It is also used for treating certain auto-immune disorders like rheumatoid arthritis and lupus. It is considerably inexpensive and is an over-the-counter medication. Let us now move deeper into understanding more about what this drug is and how it works.

Mechanism of action of Hydroxychloroquine: Hydroxychloroquine is termed as an interferon blocker and functions by minimizing the response of the immune system against a virus. This mechanism of action of hydroxychloroquine has scientists globally and is currently at the center of investigation for its effectiveness against the dreadful COVID-19 infection. An overactive reaction by the immune system is believed to be predominantly responsible for consequent pneumonia, a severe manifestation of SARS-CoV-2 infection.

Clinical outcomes with HCQ in COVID-19 patients: Initial reports from China discovered that chloroquine could stop SARS-CoV-2 in-vitro, and demonstrated seeming efficacy in treating COVID-19 in humans. However, it has yielded mixed results in the initial trials conducted in humans to test its efficacy in treating COVID 19 patients.

The experts who favor the drug’s use opine that Hydroxychloroquine (HCQ) reduces the recovery time significantly and also improved pneumonia in trials involving patients with relatively mild COVID-19 symptoms. Also, a combination of HCQ and azithromycin resulted in clinical improvement in 78/80 COVID 19 patients. However, the researchers opposing the HCQ use argue that HCQ in addition to standard care was not more effective versus only standard care in a trial carried out in 30 patients with COVID-19 in China. So, at present, one cannot confirm the effectiveness of HCQ in treating COVID 19 patients.

Concerns with the widespread use of HCQ in COVID 19 patients: Presently, whether HCQ works in vivo against any virus is not definitely proven, and actually, it is not effective at all as per outcomes of randomized controlled trials against several viruses, including influenza. However, despite the lack of strong evidence, some people are now trying to self-medicate with the drug, with fatal outcomes. Hydroxychloroquine can have hazardous side-effects related to heart rhythm irregularities, in cases of improper dose control, and cases of chloroquine poisoning have already emerged in some parts around the globe.

Hence, currently “A Wait-and-Watch Strategy” is the only way forward till reliable data favoring HCQ in COVID 19 emerges. Till then, HCQ can be used as empirical treatment, strictly under doctor’s recommendations, to ease symptoms in COVID 19 patients.

It’s been a while that the World Health Organization (WHO) declared COVID-19 as a global pandemic but unfortunately, the world is yet to see a successful antidote that can fight the virus and save lives. With more than 100 countries being affected by the virus and non-availability of any treatment, it becomes very important for you to adhere to the guidelines issued by medical authorities to stay protected.

One of the key factors in preventing yourself from the virus is by improving your immune system along with maintaining the required hygiene standards. The stronger the immune system, the greater are the chances to resist the virus. Your immune system is known for doing a remarkable job when it comes to fighting off foreign cells to protect against illnesses. Various factors play a part, such as age and lifestyle that determines how resilient the defense system will be. Naturally, when something massive like COVID-19 strikes the globe, we’re bound to feel more concerned than usual about staying strong and healthy. Hence, boosting your immunity through the following steps can aid in preventing COVID-19.

1) Consume a healthy diet:  Food is one of the principal aspects in deciding your general immunity status and health. Consumption of diet, low in carbohydrates is advisable, as it aids in controlling high blood sugar, blood pressure, and body weight. Hence, you should take green vegetables and fruits, rich in Vitamins (B and C). You can prefer consuming diets rich in good bacteria such as yogurt, curd, etc. which aids in preserving gut immunity.

2) Get ample sleep: Prefer taking sound sleep of 8 to 9 hours as it is termed as the ideal way to aid your body in boosting your immunity.

3) Stay Hydrated: Drink around 8 to 10 glasses of water preferably warm and any form of fluids daily to maintain hydration, as it helps your body to remove any toxins and decreases the risk of getting any sort of flu, even COVID-19.

4) Exercise regularly: Regular exercise for 30 to 45 minutes along with a good diet is recommended for improving metabolism which directly impacts our immune system. A mix of free weight exercises like push-ups, jumping squats or burpees can be added to the regime and performed from the comfort of your home.

5) Avoid any sort of stress: Undue stress releases stress chemicals in the body (hormone cortisol), which makes your body prone to getting infected. Meditation, avoiding self-criticism, doing your favorite hobby, or even a video call with friends can help take down stress and indirectly make you feel stronger.

6) Avoid unwanted or leisure traveling: Though travel and leisure are something that everyone should experience for recreation but not during a pandemic. Especially, when there’s a high risk to your life. Staying home is the safest option to stay protected. 

It would be hard to deny the fact that lockdown has seriously taken a big toll on the mental health of a lot of people.  While it is important to stay informed and follow all the necessary measures shared by the respective authorities, it’s even more important to manage your mental health during this isolation period. And, with lockdown getting extended again and uncertainty of the situation getting better, it is necessary to identify ways that can keep your mind stable. Factors like losing jobs, low availability of food and groceries, loneliness and uncertainties of the future are just adding to the overall stress and anxiety levels.  Following are a few tips that can help in maintaining sound mental health during this tough hour.

1) Exercise at home: Exercising every day for 30-40 minutes or even doing yoga can be a great way to take down stress. It is said that regular participation in any physical exercise helps in decreasing overall levels of tension, stress, stabilize mood and improve sleep.

2) Consume a healthy diet: Though it is easy to binge eat any food during such times, however, eating veggies, fruits and homemade items can help keep your gut health on top.

3) Get ample sleep: Adequate sleep cycle can help your mind and body to recharge and react positively to almost all kinds of situations. Also, it is great for muscle recovery and development.

4) Stop watching negative updates: While it’s important to stay updated & informed, consuming constant content on coronavirus can stress you up. Watch news related to the disease in moderation and be selective of the content you consume on TV or social media. Instead, you may follow people that inspire you or read books/articles that help you stay positive.

5) Create a balanced daily routine: A balanced work-life routine that’s aimed towards building good physical and mental health can help in increasing the overall productivity, decrease overthinking and the negative mindset. We must take short breaks at regular intervals to rewind your mind.

6) Walking in your home space after regular intervals: Like any other cardiovascular exercise, walking also can boost endorphins, which can reduce stress hormones and alleviate mild depression.

7) Get enough oxygen/fresh air: Standing in your balcony and enjoying the fresh air is a great way to switch off your mind and soak in the goodness. This way you not only breathe in some fresh air but also helps in feel light-hearted.

8) Conversation with friends: Talk to your friends or relatives if anything bothers you because sharing what you feel with your loved ones can make you feel relaxed and give a feeling of extra support. 

With the spread of the COVID-19 comes a lot of panic and fear and that’s not it. Along with that, there’s a great amount of misinformation that’s been shared all over. From the origin of the virus to transmission to preventive measures, every aspect has some of the other misinformation attached to it. And, if we want to seriously fight the deadly COVID-19, it is important to first have the detailed and correct information regarding the same. Spreading misinformation and half-knowledge will only add on to the misery and anxiety levels.

Let us now learn a few facts about COVID-19 and clear all the myths surrounding it.

MYTH 1: COVID 19 can transmit through the air and spread through mobile networks

FACT: COVID 19 does not spread through mobile networks or air transmission. Viruses cannot travel on radio waves. COVID 19 is spreading in many areas without mobile networks. COVID 19 can be spread only via respiratory droplets when an infected person coughs, sneezes, or speaks. People can also be infected by touching a contaminated surface and then their eyes, mouth, or nose. This is the main reason why the focus is being given to social distancing.

MYTH 2: COVID 19 virus cannot survive under sun exposure or temperature above 25 degrees Celsius

FACT: This is a myth. You can get infected with COVID-19 no matter how hot the climate is or the strength of sunshine.

MYTH 3: All patients can recover from the disease

FACT:  Most of the COVID 19 patients can recover from the COVID-19 infection. But, patients who are at an advanced age or are suffering from chronic conditions such as diabetes, hypertension, respiratory diseases, etc can even die due to weak immune systems.

MYTH 4: If you can hold your breath for 10 seconds means you don’t have COVID-19 infection

FACT: Having the capacity to hold your breath for more than 10 seconds does not mean you don’t have COVID-19. Dry cough, fatigue and fever are the most common symptoms of the infection. Some patients may develop more severe forms such as pneumonia. The best and the only way to confirm if you have COVID-19 disease is with a laboratory test.

MYTH 5: Alcohol consumption can save against COVID-19

FACT: Drinking alcohol cannot save you against COVID-19 instead it is dangerous and can increase the risk of health problems.

MYTH 6: Extreme cold weather can kill COVID-19 virus

FACT: Extreme cold temperature or snowfall cannot kill the virus as irrespective of the atmospheric changes, the human body temperature remains steady.

MYTH 7: Taking a shower under hot water prevents COVID-19 infection

FACT: Taking a hot shower does not alter the body temperature as your normal body temperature remains around 36.5°C to 37°C, regardless of the temperature of your bath or shower. Taking an extremely hot shower can, on the contrary, cause skin problems.

MYTH 8: The COVID 19 infection can be transmitted through mosquito bites

FACT:  COVID 19 viral infection is not a mosquito-borne infection such as malaria or dengue. The new coronavirus is a respiratory virus which spreads primarily through droplets generated when an infected person coughs or sneezes, or through droplets of saliva or discharge from the nose.

MYTH 9: Hand dryers are effective in killing the COVID-19 virus

FACT: Hand dryers are ineffective in killing the COVID 19 infection. Only frequent hand washing with soap water or sanitizer will help.

MYTH 10: UV lamps should be used for hand sterilization

FACT: Ultra-violet (UV) lamps should not be used for hand sterilization as UV radiation can lead to skin irritation and damage your eyes.

MYTH 11: Thermal scanning detects all COVID-19 patients

FACT: Thermal scanners can only detect COVID 19 infection in patients who have a fever. Asymptomatic patients cannot be identified.

MYTH 12: Pneumonia vaccines help prevent COVID-19

FACT: No. Pneumonia vaccines cannot protect the novel coronavirus. It needs inventing a new vaccine, dedicated to the virus.

MYTH 13: Regular nose rinsing with saline water protects against COVID 19

FACT: No. There is an absence of any evidence confirming that regularly rinsing the nose with saline has protected people from infection with the new coronavirus.

MYTH 14: Garlic consumption can save against coronavirus

FACT: Garlic eating cannot help against COVID -19, though being a healthy food with anti-microbial properties.

MYTH 15: COVID 19 only affects the elderly

FACT: COVID 19 affects only aged patients is a myth. Persons belonging to all age groups are susceptible to get this infection. Older people or people with pre-existing medical conditions are more vulnerable to getting infected hence advised to take precautions to protect themselves from the virus.

MYTH 16: Antibiotics can treat COVID-19 infections

FACT: COVID 19 disease is a viral outbreak. Hence, no antibiotic, can work against it. Antibiotics can only be used against bacteria.

MYTH 17: Treatment for COVID-19 infection exists/is now available

FACT: Until now, no medicine is capable of preventing or treating the new coronavirus.

MYTH 18: Spraying chlorine or alcohol all over the body can prevent COVID 19 infections

FACT:  Alcohol or chlorine sprayed on the body cannot save you from the virus that has already entered the body. These can be poisonous and cause irritation and damage to the skin.

Grocery stores are one of the only few places where we are allowed to go during the lockdown. Though this news manages to put a smile on your face every time but somewhere also raises a question that are you unintentionally putting yourselves and your families at risk after a round- trip to the grocery shop? Honestly, there’s nothing much that you can do about this because we all need to eat food to live and no matter how risky it gets someone from our families will have to step out and do it.

With WHO clearly stating that there are high chances of the virus surviving on the surfaces for few days and can be transmitted through the same, it becomes even more crucial to understand the need of the hour. The earlier you accept the fact that it is going be crowded every time you visit a grocery store the better it is. People are going to sweep the supermarket shelves irrespective of what the government says on the availability of the essential items and hence it makes it even more important for you to follow every precautionary measure whenever you are out for a grocery shopping.

Below are a few safety tips that you can follow when you step out of the house next time to buy groceries:

1) Maintain at least six-feet distance from other customers.

2) Don’t shake hands or have any form of physical contact with the customers or the shopkeeper.

3) Wipe the carts or basket handles with disinfectant wipes.

4) Avoid touching your face.

5) Always keep your face mask worn.

6) Carry your hand sanitizer and use it while waiting at the counter and after leaving the store.

7) Avoid going to the store if you are sick.

8) Wash your hands after unpacking the items.

9) If possible, prefer home delivery of groceries with proper precaution.

10) Rinse fruits and vegetables with warm water and baking soda before using them.

The mere thought of getting a cardiac arrest can make your heart beat faster for a moment. But today, even if a heart attack is a perilous event, there are many ways to circumvent the same.

Angioplasty or stenting is one such lifesaver option, especially when performed right after a heart attack. Putting in a stent helps prevent the narrowing of arteries and substantially improve your blood flow and prevent further damage to your heart. Many patients undergo Angioplasty once they are diagnosed with coronary artery disease. Mainly, because of two reasons: a doctor suggesting it because of its high success rate and less invasive technique and secondly it improves the lifestyle significantly by reducing the risk of getting another heart attack.

Now, let us go deeper into understanding what these stents are and how can they help reduce further problems.

Stents are tiny mesh tubes inserted to keep coronary blood vessels (arteries) open post angioplasty. The coronary arteries are responsible for carrying blood and oxygen to heart muscle cells. A heart attack often occurs when plaque breaks open and causes the formation of a blood clot in a partially clogged artery eventually blocking the blood flow. This is when stenting comes in the picture and can be a lifesaver option. Stents come in various forms but DES (Drug Eluting Stent) is the most commonly used ones during Angioplasty worldwide.

After implantation, DES releases a drug gradually from its outer coating to aid in preventing blockage at the particular site. Hence, DES are preferred over BMS (Bare Metal Stent) for the majority of the patients as they prevent recurring blockages in the arteries.  Also, the recent DES are termed to be at least as safe as BMS. However, there are chances blood vessels could again get blocked after stent placement. In the case of BMS, post-implantation as the vessel heals, tissue begins to grow around the stent but in some cases, such scar tissue overgrowth can lead to re-blockage of the vessel. However, a DES implantation can avoid this phenomenon as it prevents scar tissue formation thus maintaining proper blood flow. But, you will require to regularly take blood-thinning medicines to avoid blood clot formation in the stent and prevent the blood vessel from getting blocked again. There are various DES & BMS brands available and they come with their own set of benefits and a cardiologist may suggest one to you based on the requirement.

In simple words, Drug-Eluting Stent is effective and can reduce the chances of future heart attacks to some extent. But, remember that stenting can be a life-saver option only if you continue with suggested medication and lifestyle modification like eating healthy food, regular exercise, etc. that your doctor has advised you to follow post the angioplasty.

Want to adopt a heart-healthy diet post angioplasty, but aren’t sure where to start?
One way to begin is by giving a complete makeover to your current diet plan. Focus on making meal plans that emphasize vegetables, fruits and other necessary products with an adequate amount of proteins, carbohydrates and other nutrients. We know, that the main question here is about what exactly to consume and what to avoid post implanting a stent as you may not be that well versed with every food category and ingredients benefiting a person. Hence, we have stated below foods to intake and to avoid after implanting a stent.

Firstly, it is very important that you consult a doctor before jumping onto conclusions and making your diet plans, especially after angioplasty. It is important to understand that each one of us is built differently and one particular diet plan isn’t going to work for all of us. And, hence we believe that even minor differences in your diet post angioplasty can make a huge difference to your heart health. Now, let us read more about it.

  • Consume more whole-grain foods every day: Eating whole grains is associated with various benefits, including a lower risk of diabetes, heart disease, and high blood pressure. They are rich in nutrients, minerals, fibers, antioxidants and has also proven to reduce the risk of a heart attack.
  • Eat more quantities and varieties of fruits and vegetables: People who eat more vegetables and fruits as part of an overall healthy diet are likely to have a reduced risk of some chronic diseases like stroke, cancer, diabetes, influenza or any respiratory disease. They provide nutrients vital for health and maintenance of your body.
  • Reduce salt and sugar intake: Salt and sugar are needed for health. However, we require very little of it to survive. While salt is essential for the transmission of nerve impulses and normal cell function, sugar is a real source of energy with glucose being the most important of all. But, due to rapid urbanization and changing lifestyles, dietary patterns have seen a major shift and processed foods are being consumed more which is indirectly increasing the risk of heart diseases and strokes due to the high amount of salt and sugar content in it. And, for a person who has just undergone Angioplasty, it becomes highly important to maintain a healthy balance of salt and sugar to avoid any further heart illnesses.
  • Cut down on the consumption of fatty foods, rich in LDL, trans fats and saturated fats: Eliminate fatty meats like pork, lamb or fried items, butter, or coconut oil from your diet. There are two main types of potentially harmful dietary fats, trans fat and saturated fat. These types come mainly from animal sources of food, such as red meat, poultry and full-fat dairy products especially whole milk. They raise high-density lipoprotein (HDL or “good”) cholesterol and low-density lipoprotein (LDL or “bad”) cholesterol levels, which may increase your risk of cardiovascular disease.
  • Include good fats in your diet: Dietary fats are important for your body as it is responsible for supplying energy and to support cell growth. They also help in protecting your organs and help in absorbing nutrients and produce important hormones. The simplest way to differentiate good and bad fats is, good fats remain in liquid form at room temperature. Monounsaturated fats and polyunsaturated fats are known as “good fats” because they are good for your heart, cholesterol, and overall health. Some of these sources are nuts, olives, flax seeds, fish oils, etc. Bad fats are of two types, Saturated fat and Trans fat and these have been identified as potentially harmful to your health. Most of the foods that contain these types of fats are solid at room temperatures, such as butter, coconut/palm oil, margarine, beef or pork fat, etc.
  • Fish and lean meat are good options for individuals taking non-vegetarian meals: Lean meats and fish have relatively low-fat content and have high amounts of protein. Protein is an essential part of a balanced diet. Beyond protein’s essential roles in building and maintaining muscle and tissues in your body and helping regulate many body processes, it also promotes satiety fullness and may help in managing your weight.
  • Avoid consumption of red meat: Red meats (beef, pork and lamb) have more saturated (bad) fat than chicken, fish and vegetable proteins such as beans. Saturated and trans fats can raise blood cholesterol and make heart diseases worse.

Finally, remember that a healthy diet is a mixture of all foods you eat and not only power foods that you think are filled with necessary nutrients. Having the right mix of everything (protein, fats, carbohydrates and other nutrients) after Angioplasty is always regarded as healthy. So, speak to your cardiologist, get expert advice on it and work towards building meals that are aimed towards a better and faster recovery.

Have you ever thought about why you often fall sick? Do you think it’s the climate change or overexertion that makes you feel weak and eventually fall sick? You may be right but you wouldn’t want to play the blame game every time because not everyone whom you know is falling sick that often but it’s only you. So, how do we go about it and change this phenomenon of your body?

Firstly, it is important to know the defense system of our body before jumping on to activities strengthening it. Our immune system is a host defense system comprising many biological structures and processes within the body that protects against disease and potential health hazards.  When functioning properly, the immune system can identify multiple threats like viruses, bacteria and parasites and works towards distinguishing them from the body’s healthy tissue. As long as your immune system is running efficiently, you don’t notice that it’s doing the job, however, the moment it stops working properly or becomes weak to fight harmful substances, you get ill.

Hence, it becomes very crucial for you to follow measures that can boost your immunity system. Because healthier the immunity system, healthier are you. We have listed below a few tips that can play a vital role in boosting your overall immunity. Take a look and incorporate those in your lifestyle to stay healthy and fit.

Hip pain is not normal and can cause serious trouble if not treated wisely. Any discomfort or painful sensation near the thighbone or pelvic girdle can be termed as hip pain. The hip joint is a ball and socket synovial joint that is responsible for providing a wide range of motion for the lower torso. It is because of the hip joint one can stand, walk, dance or lift. It is also considered as one of the most important joint when it comes to stability. However, as the person ages, the joint may undergo wear and tear.

Though hip pain to an extent can be treated with medication, injections and physical therapy, hip replacement surgery is the safest and the best option to treat hip-related problems when nothing else finds success in relieving the pain. A hip replacement could be recommended to any patient, in case they are suffering from chronic hip pain which is hindering their daily activities and other non-invasive methods of pain reduction have proved to be ineffective or are no longer effective to improve their condition. A patient with symptoms of severe hip arthritis, including as stated below, could be suggested to go for Hip replacement surgery.

1) Hip pain: An aching hip can make any patient’s life miserable. The most vital factor in selecting to have a hip replacement is quantifying the extent to which pain is affecting a patient. Pain that leads to interference in performing daily activities, even not letting anyone have a sound sleep, and is restricted between hip and knee could indicate arthritis of the hip. Some patients need the support of a cane or are also seen limping. A set of such patients regularly rely on pain-killer consumption to deal with their pain. In such cases, doctors usually suggest a patient with a replacement surgery to get long-lasting relief.

2) Stiffness: Difficulty in performing certain normal activities like doing weight training, cycling or even bending down for picking basic objects

3) Sprain: A sprain in a muscle occurs when the ligament is stretched than the usual limit causing the area to swell. A sprain can be caused by any sudden fall, twist, and turn of the muscle groups/joints.

 4) Difficulty in weight-bearing: In case a patient is not able to stand on his/her paining leg even for a minute with support, it indicates that their hip’s condition is very bad and they need a total hip replacement surgery.

5) Muscle stress: When the body is stressed, muscles tense up. Muscle tension is the body’s way of guarding against injury and pain. For e.g when you sit in one position for some time, you may end up making them stressed. This causes a change in the body’s nervous system by contracting blood vessels and reducing blow flow.

6) Fractures. A hip fracture is a fracture of the upper region of the femur or the thighbone. Fractures lead to swelling, difficulty in walking, sitting, etc causing severe pain.

Also, if the patient is suffering from Osteoarthritis or Osteoporosis, they can be advised to undergo a Total Hip Replacement. With Osteoarthritis, the joints become stiff and swollen due to inflammation and a breakdown of cartilage, causing pain and deformity are observed. Talking about Osteoporosis, it is a bone disease that occurs when the body loses too much bone, makes too little bone, or both.

So, in case you are experiencing severe pain with no sign of pain killers bailing you out of the dreadful situation, a hip replacement surgery then can be regarded as the best treatment option. Remember that the surgery option should only be considered when all other conservative treatment options have failed to provide relief from continuous hip pain and restricted mobility.

Also, remember that whatever the cause is, hip pain is more common as you grow older. And over time, your joint will see a lot of wear and tear. So make sure you are taking adequate care of the joints by eating healthy and doing the right exercises to keep your bone health at its best. 

Although it looks as if the pandemic is affecting almost everyone in some or other way, it may be even more crucial for people suffering from hypertension to stay updated and informed about COVID 19. Doctors suggest that coronavirus infection can be more fatal in those with hypertension and also alter the action of antihypertensive drugs.

The outbreak of COVID 19 is indeed more vital for hypertensive patients. Present data confirms that hypertensive patients are at elevated risk of getting COVID 19. Also, such patients carry a higher risk of needing hospitalization, ventilation requirement and even death. As per WHO, hypertensive patients fall under the highest-risk category for getting affected by more severe COVID 19 cases and even death. The COVID 19 death rate in hypertensive patients is 8.4% vs. 0.9% in patients without any pre-existing condition. Two special implications have been found for hypertension and COVID 19:

  • Hypertensive patients have elevated ACE2 levels
  • Hypertensive patients on ACE inhibitors or ARB therapy may need to stop taking these medications or need re-evaluation if they contract COVID 19.

Hypertensive patients require to follow the same precautionary measures as normal individuals to prevent getting the infection, apart from keeping their BP in check.

  1. Maintain your recommended blood sugar and blood pressure levels.
  2. Frequently monitor your blood sugar and BP levels to rapidly identify any irregularities and get appropriate treatment adjustments.
  3. Get enough supplies related to your co-morbid testing and medications, in case of an outbreak, for at least 15 days.
  4. Practice frequent handwashing with soap and water.
  5. Practice good respiratory hygiene by covering your mouth and nose with a tissue or bent elbow, in case of coughing or sneezing.
  6. Avoid touching your face, nose, and eyes.
  7. Avoid unwanted travel and socializing.
  8. Stay vaccinated for each available infectious disease.
  9. Eat plenty of fruits and vegetables.
  10. Consume yogurt and probiotics for a healthy digestive system.
  11. Sleep for at least 8-9 hours to reduce stress and maintenance of immunity levels.
  12. Avoid crowd exposure and handshaking.
  13. Immediately contact your doctor if you develop any respiratory symptoms such as cold, cough, difficulty in breathing or fever.
  14. Last but not the least, stay hydrated.